Cisapride-d6 is a deuterium-labeled analogue of Cisapride, primarily functioning as a stable isotope for analytical applications. As a 5-HT4 receptor agonist with an EC50 of 140 nM, Cisapride enhances gastrointestinal motility, making it a valuable gastroprokinetic agent. Additionally, it acts as a hERG blocker with an IC50 value of 9.4 nM, facilitating research into cardiac safety profiles. This reagent is ideal for studying pharmacokinetics and metabolic pathways in preclinical models.
Cisapride-d6 is a deuterium-labeled analogue of Cisapride, primarily functioning as a stable isotope for analytical applications. As a 5-HT4 receptor agonist with an EC50 of 140 nM, Cisapride enhances gastrointestinal motility, making it a valuable gastroprokinetic agent. Additionally, it acts as a hERG blocker with an IC50 value of 9.4 nM, facilitating research into cardiac safety profiles. This reagent is ideal for studying pharmacokinetics and metabolic pathways in preclinical models.
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