Fig. 1 · Structure
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CJ-13,610 hydrochloride
Cat. No.
A76464
CAS
179420-27-0
5-lipoxygenase Inhibitor
CJ-13,610 hydrochloride is a potent and orally active nonredox-type inhibitor of 5-lipoxygenase, exhibiting an IC50 value of 0.07 μM. By competing with activating lipid hydroperoxides at a key regulatory binding site, it effectively prevents 5-lipoxygenase catalysis. This reagent is valuable for research into conditions associated with increased 5-lipoxygenase activity, including inflammatory disorders, allergic asthma, cancer, and atherosclerosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 179420-27-0 |
| Applications | 5-lipoxygenase Inhibitor |
| Formula | C22H24ClN3O2S |
| Molecular Weight | 429.96 |
| SMILES | NC(C1(C2=CC(SC3=CC=C(N4C(C)=NC=C4)C=C3)=CC=C2)CCOCC1)=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.