CJ-13,610 hydrochloride is a potent and orally active nonredox-type inhibitor of 5-lipoxygenase, exhibiting an IC50 value of 0.07 μM. By competing with activating lipid hydroperoxides at a key regulatory binding site, it effectively prevents 5-lipoxygenase catalysis. This reagent is valuable for research into conditions associated with increased 5-lipoxygenase activity, including inflammatory disorders, allergic asthma, cancer, and atherosclerosis.
CJ-13,610 hydrochloride is a potent and orally active nonredox-type inhibitor of 5-lipoxygenase, exhibiting an IC50 value of 0.07 μM. By competing with activating lipid hydroperoxides at a key regulatory binding site, it effectively prevents 5-lipoxygenase catalysis. This reagent is valuable for research into conditions associated with increased 5-lipoxygenase activity, including inflammatory disorders, allergic asthma, cancer, and atherosclerosis.
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