CL2A acid

Name: CL2A acid
Brand: Adooq Bioscience
SKU: A18396
Rating: 5 (288 reviews)

Catalog No.: A18396

L2A is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker.

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Grouped product items
Size	Price	Stock
1mg	$320.00	In stock
5mg	$960.00	In stock
10mg	$1,600.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	L2A is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker.

Product Information

Catalog Num	A18396
Formula	C51H79N9O18
Molecular Weight	1106.22
CAS Number	1846605-04-6
SMILES	O=C(NC1=CC=C(COC(O)=O)C=C1)[C@H](CCCCN)NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN2N=NC(CNC(C3CCC(CN4C(C=CC4=O)=O)CC3)=O)=C2)=O)=O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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