Clobetasol 17-Propionate-d5 is a deuterium-labeled derivative of Clobetasol propionate, a potent and selective inhibitor of CYP3A5, exhibiting an IC50 of 0.206 μM. This compound specifically targets CYP3A5 while showing no inhibition on CYP3A4 or other major cytochrome P450 enzymes. With its corticosteroid properties, Clobetasol 17-Propionate-d5 is suitable for research applications related to psoriasis and other dermatoses, providing a valuable tool for studying the pharmacokinetics and metabolism of corticosteroids in biological systems.
Clobetasol 17-Propionate-d5 is a deuterium-labeled derivative of Clobetasol propionate, a potent and selective inhibitor of CYP3A5, exhibiting an IC50 of 0.206 μM. This compound specifically targets CYP3A5 while showing no inhibition on CYP3A4 or other major cytochrome P450 enzymes. With its corticosteroid properties, Clobetasol 17-Propionate-d5 is suitable for research applications related to psoriasis and other dermatoses, providing a valuable tool for studying the pharmacokinetics and metabolism of corticosteroids in biological systems.
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