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Ramelteon metabolite M-II-d3

Catalog No.: A61721
Stable Isotope
Ramelteon metabolite M-II-d3 is a deuterium-labeled derivative of the major metabolite M-II of Ramelteon, a selective agonist of melatonin receptors (MT1 and MT2). This reagent exhibits significant biological activity, with IC50 values of 208 pM and 1470 pM for human MT1 and MT2 receptors, respectively. It is primarily used in pharmacological studies and metabolic research involving melatonin signaling pathways.
Ramelteon metabolite M-II-d3 1246812-22-5 Stable Isotope
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1mg
$190.00
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5mg
$500.00
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRamelteon metabolite M-II-d3 is a deuterium-labeled derivative of the major metabolite M-II of Ramelteon, a selective agonist of melatonin receptors (MT1 and MT2). This reagent exhibits significant biological activity, with IC50 values of 208 pM and 1470 pM for human MT1 and MT2 receptors, respectively. It is primarily used in pharmacological studies and metabolic research involving melatonin signaling pathways.
Product Information
Catalog NumA61721
FormulaC16H18D3NO3
Molecular Weight278.36
CAS Number1246812-22-5
SMILES[2H]C([2H])([2H])C(O)C(NCC[C@H]1C2=C(CC1)C=CC3=C2CCO3)=O
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Isotope-Labeled Compounds