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Colchicine-d3

Catalog No.: A31215
Stable Isotope
Colchicine-d3 is a deuterium-labeled derivative of colchicine, a potent inhibitor of tubulin that disrupts microtubule dynamics. It exerts its primary biological activity by inhibiting microtubule polymerization at an IC50 of 3 nM. Additionally, colchicine acts as a competitive antagonist of α3 glycine receptors (GlyRs), making it valuable for various research applications in cell biology and neurobiology.
Colchicine-d3 1217625-62-1 Stable Isotope
Grouped product items
Size Price Stock Qty
1mg
$575.00
In stock
5mg
$1,475.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionColchicine-d3 is a deuterium-labeled derivative of colchicine, a potent inhibitor of tubulin that disrupts microtubule dynamics. It exerts its primary biological activity by inhibiting microtubule polymerization at an IC50 of 3 nM. Additionally, colchicine acts as a competitive antagonist of α3 glycine receptors (GlyRs), making it valuable for various research applications in cell biology and neurobiology.
Product Information
Catalog NumA31215
FormulaC22H22D3NO6
Molecular Weight402.46
CAS Number1217625-62-1
SMILESCOC1=C2C(C([C@H](CCC2=CC(OC)=C1OC)NC(C([2H])([2H])[2H])=O)=C3)=CC=C(OC)C3=O
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Isotope-Labeled Compounds