Colchicine-d6 is a deuterium-labeled analogue of colchicine, a potent tubulin inhibitor and microtubule-disrupting agent. It inhibits microtubule polymerization with an IC50 value of 3 nM, making it a valuable tool for studying cytoskeletal dynamics. Additionally, colchicine-d6 acts as a competitive antagonist of α3 glycine receptors, facilitating research into the role of microtubule stability and glycine receptor modulation in various biological processes.
Colchicine-d6 is a deuterium-labeled analogue of colchicine, a potent tubulin inhibitor and microtubule-disrupting agent. It inhibits microtubule polymerization with an IC50 value of 3 nM, making it a valuable tool for studying cytoskeletal dynamics. Additionally, colchicine-d6 acts as a competitive antagonist of α3 glycine receptors, facilitating research into the role of microtubule stability and glycine receptor modulation in various biological processes.
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