Fig. 1 · Structure
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Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:19)
Antimicrobial Agent
Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:19) is an antimicrobial agent that combines Trimethoprim and Sulfamethoxazole in a ratio of 1:19. This synergistic formulation effectively targets bacterial dihydrofolate reductase and inhibits folate synthesis, leading to bactericidal activity. It is commonly employed in research applications focusing on treating bacterial infections and studying antimicrobial resistance mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 8064-90-2 |
| Applications | Antimicrobial Agent |
| Formula | C24H29N7O6S |
| Molecular Weight | 543.60 |
| SMILES | O=S(NC1=NOC(C)=C1)(C2=CC=C(C=C2)N)=O.NC3=NC=C(CC4=CC(OC)=C(C(OC)=C4)OC)C(N)=N3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.