Fig. 1 · Structure
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CP-346086 dihydrate
MTP Inhibitor
CP-346086 dihydrate is a potent inhibitor of microsomal triglyceride transfer protein (MTP), with an IC50 of 2.0 nM for both human and rodent MTP. This compound effectively reduces plasma cholesterol and triglyceride levels in vivo, making it a valuable tool for research into lipid metabolism and cardiovascular disease. Its oral bioavailability enhances its utility in pharmacological studies related to lipid disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1262769-98-1 |
| Applications | MTP Inhibitor |
| Formula | C26H26F3N5O3 |
| Molecular Weight | 513.51 |
| SMILES | O=C(C1=CC=CC=C1C2=CC=C(C(F)(F)F)C=C2)NC3=CC4=C(CN(CC5=NC=NN5)CC4)C=C3.[H]O[H].[H]O[H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.