Fig. 1 · Structure
Documents & Downloads
CP-346086
MTP Inhibitor
CP-346086 is a potent inhibitor of microsomal triglyceride transfer protein (MTP), exhibiting an IC50 of 2.0 nM for both human and rodent MTP. This compound effectively reduces plasma cholesterol and triglyceride levels in vivo, making it a valuable tool for studying lipid metabolism and cardiovascular diseases. Its pharmacological properties position CP-346086 as a significant reagent for research into dyslipidemia and related metabolic conditions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 186390-48-7 |
| Applications | MTP Inhibitor |
| Formula | C26H22F3N5O |
| Molecular Weight | 477.48 |
| SMILES | O=C(C1=CC=CC=C1C2=CC=C(C(F)(F)F)C=C2)NC3=CC4=C(CN(CC5=NC=NN5)CC4)C=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.