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Crabrolin

Antimicrobial Agent

Crabrolin is a tridecapeptide derived from the venom of the European hornet (Vespa crabro) and functions as an antimicrobial agent. It demonstrates significant antibacterial activity, exhibiting minimum inhibitory concentrations (MIC) and minimum bactericidal concentrations (MBC) of 2/2 μM against S. aureus (NCTC 10788), 16/64 μM against MRSA (NCTC 12493), and 4/8 μM against E. faecium (NTCC 12697). This compound is useful for research applications focused on the development of new antimicrobial therapies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	93207-22-8
Applications	Antimicrobial Agent
Formula	C₇₄H₁₃₀N₁₈O₁₄
Molecular Weight	1495.94
SMILES	C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)C)=O)[C@@H](C)O)=O)[C@@H](C)C)=O)[C@H](CC)C)=O)CCCCN)=O)CCCNC(=N)N)=O)CC(C)C)=O)[C@H](CC)C)=O)CC(C)C)(=O)[C@H]1N(C([C@@H](NC([C@H](CC2=CC=CC=C2)N)=O)CC(C)C)=O)CCC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.