CRT 0105446

Catalog No.: A54787
LIMK1 Inhibitor
CRT 0105446 is a selective inhibitor of LIMK1, exhibiting an IC50 value of 8 nM. This compound is valuable for investigating the role of LIMK1 in cellular processes such as cytoskeletal dynamics and cell migration. Researchers can utilize CRT 0105446 to explore its effects in studies related to cancer, neurodegenerative diseases, and other conditions where LIMK1 modulation is implicated.
Grouped product items
Size Price Stock Qty
1mg
$75.00
In stock
5mg
$225.00
In stock
10mg
$325.00
In stock
25mg
$555.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCRT 0105446 is a selective inhibitor of LIMK1, exhibiting an IC50 value of 8 nM. This compound is valuable for investigating the role of LIMK1 in cellular processes such as cytoskeletal dynamics and cell migration. Researchers can utilize CRT 0105446 to explore its effects in studies related to cancer, neurodegenerative diseases, and other conditions where LIMK1 modulation is implicated.
Product Information
Catalog NumA54787
FormulaC20H18F3N3O2S
Molecular Weight421.44
CAS Number1661846-05-4
SMILESCC(C(NC1=NC=C(S1)C2=C(C=NC=C2)C3=CC=C(C=C3C(F)(F)F)OC)=O)C
Useful Calculator

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