TH470 is a highly selective inhibitor of LIMK1 and LIMK2, exhibiting IC50 values of 9.8 nM and 13 nM, respectively. This compound effectively modulates the actin cytoskeleton and related cellular processes by inhibiting LIM kinase activity. TH470 is particularly valuable in the study of orphan diseases and other conditions related to dysregulated LIMK signaling.
TH470 is a highly selective inhibitor of LIMK1 and LIMK2, exhibiting IC50 values of 9.8 nM and 13 nM, respectively. This compound effectively modulates the actin cytoskeleton and related cellular processes by inhibiting LIM kinase activity. TH470 is particularly valuable in the study of orphan diseases and other conditions related to dysregulated LIMK signaling.
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