SR7826 is a potent and selective LIMK1 inhibitor, exhibiting an IC50 of 43 nM. This bis-aryl urea derivative demonstrates over 100-fold selectivity for LIMK1 compared to ROCK and JNK kinases. SR7826 serves as a valuable tool for investigating LIMK1-related signaling pathways and its role in cellular processes such as cytoskeletal dynamics and cancer progression.
SR7826 is a potent and selective LIMK1 inhibitor, exhibiting an IC50 of 43 nM. This bis-aryl urea derivative demonstrates over 100-fold selectivity for LIMK1 compared to ROCK and JNK kinases. SR7826 serves as a valuable tool for investigating LIMK1-related signaling pathways and its role in cellular processes such as cytoskeletal dynamics and cancer progression.
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