CS587

Catalog No.: A78507
CaMK1D Inhibitor
CS587 is a selective inhibitor of Calcium/calmodulin-dependent protein kinase 1D (CaMK1D), demonstrating neurocytotoxic effects at concentrations of 10 μM. This compound modulates neuronal cell sensitivity to amyloid-beta (Aβ) oligomer toxicity, making it a valuable tool for studying neurodegenerative disorders and related cellular pathways. Its specificity and mechanism of action position CS587 as a significant reagent for research into neuronal health and disease mechanisms.
Grouped product items
Size Price Stock Qty
5mg
$390.00
In stock
10mg
$640.00
In stock
25mg
$1,260.00
In stock
50mg
$1,970.00
In stock
100mg
$3,070.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCS587 is a selective inhibitor of Calcium/calmodulin-dependent protein kinase 1D (CaMK1D), demonstrating neurocytotoxic effects at concentrations of 10 μM. This compound modulates neuronal cell sensitivity to amyloid-beta (Aβ) oligomer toxicity, making it a valuable tool for studying neurodegenerative disorders and related cellular pathways. Its specificity and mechanism of action position CS587 as a significant reagent for research into neuronal health and disease mechanisms.
Product Information
Catalog NumA78507
FormulaC24H30N8O
Molecular Weight446.55
CAS Number2388506-69-0
SMILESNC(C1=CN=C(N2C[C@H](CCC2)N)N=C1NC3=CC(C(C)(C)C#N)=CC(C(C)(C)C#N)=C3)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2