Cy3-NO2-Tre is a nitroreductase-responsive cyanine-based fluorescent dye designed for the specific labeling of Mycobacterium tuberculosis (Mtb). Upon activation by the conserved nitroreductase Rv3368c found in the Mycobacteriaceae family, it exhibits fluorescence, facilitating the imaging of mycobacteria within infected host cells. This fluorescent probe is valuable for tracking infection dynamics and visualizing the endocytosis of Mycobacterium smegmatis by macrophages, with excitation/emission wavelengths of 540-550/575-625 nm.
Cy3-NO2-Tre is a nitroreductase-responsive cyanine-based fluorescent dye designed for the specific labeling of Mycobacterium tuberculosis (Mtb). Upon activation by the conserved nitroreductase Rv3368c found in the Mycobacteriaceae family, it exhibits fluorescence, facilitating the imaging of mycobacteria within infected host cells. This fluorescent probe is valuable for tracking infection dynamics and visualizing the endocytosis of Mycobacterium smegmatis by macrophages, with excitation/emission wavelengths of 540-550/575-625 nm.
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