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Other Forms

Form	MW
Cytostatin This page	428.46
Cytostatin sodium	450.44

Cytostatin

PP2A Inhibitor

Cytostatin is a selective inhibitor of protein phosphatase 2A (PP2A), exhibiting an IC50 of 210 nM. This compound demonstrates significant anti-metastatic properties and possesses potent antitumor effects by inducing apoptosis in cancer cells. Additionally, Cytostatin effectively prevents the adhesion of B16 melanoma cells to extracellular matrix components such as laminin and collagen, highlighting its potential for research in cancer biology and therapeutic applications. Cytostatin is classified within the natural product family of fosriecin.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	682329-63-1
Applications	PP2A Inhibitor
Formula	C₂₁H₃₃O₇P
Molecular Weight	428.46
SMILES	O=C1C=C[C@H](C)[C@H]([C@@H](C)CC[C@H](OP(O)(O)=O)[C@@H](C)[C@@H](O)/C=C\C=C/C=C/C)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.