DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS

Catalog No.: A44559
Fluorescent Dye
DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye utilized as a fluorogenic substrate for aspartyl proteinases derived from human malaria parasites. This compound exhibits enhanced fluorescence upon cleavage, making it an effective tool in studying enzyme activity and kinetics. Its applications extend to research focusing on malaria pathogenesis and the development of potential therapeutic strategies against the disease.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye utilized as a fluorogenic substrate for aspartyl proteinases derived from human malaria parasites. This compound exhibits enhanced fluorescence upon cleavage, making it an effective tool in studying enzyme activity and kinetics. Its applications extend to research focusing on malaria pathogenesis and the development of potential therapeutic strategies against the disease.
Product Information
Catalog NumA44559
FormulaC76H98N16O15S
Molecular Weight1507.75
CAS Number263718-22-5
SMILESN(CCNC(=O)[C@H]1N(C([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)C4=CC=C(N=NC5=CC=C(N(C)C)C=C5)C=C4)CCC(O)=O)=O)CCCNC(=N)N)=O)CCCC)=O)=O)CC(C)C)=O)CO)=O)=O)CCC1)C=6C7=C(C(S(=O)(=O)O)=CC=C7)C=CC6
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