Dabigatran-13C6 is a stable isotope-labeled form of Dabigatran, a potent oral anticoagulant that functions as a reversible, competitive direct thrombin inhibitor with a Ki of 4.5 nM. It effectively inhibits thrombin-induced platelet aggregation, demonstrating an IC50 of 10 nM. This reagent is valuable for pharmacokinetic studies and metabolic profiling in anticoagulant research, enabling precise tracking of drug dynamics in biological systems.
Dabigatran-13C6 is a stable isotope-labeled form of Dabigatran, a potent oral anticoagulant that functions as a reversible, competitive direct thrombin inhibitor with a Ki of 4.5 nM. It effectively inhibits thrombin-induced platelet aggregation, demonstrating an IC50 of 10 nM. This reagent is valuable for pharmacokinetic studies and metabolic profiling in anticoagulant research, enabling precise tracking of drug dynamics in biological systems.
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