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Dabigatran etexilate-d11

Catalog No.: A77909
Stable Isotope
Dabigatran etexilate-d11 is a stable isotope-labeled form of Dabigatran etexilate, a prodrug that acts as a direct inhibitor of thrombin. This compound exhibits potent anticoagulant properties and is primarily utilized in research involving venous thromboembolism and stroke prevention in patients with atrial fibrillation. The deuterium labeling facilitates advanced metabolic studies and pharmacokinetic assessments.
Dabigatran etexilate-d11 2469006-94-6 Stable Isotope
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDabigatran etexilate-d11 is a stable isotope-labeled form of Dabigatran etexilate, a prodrug that acts as a direct inhibitor of thrombin. This compound exhibits potent anticoagulant properties and is primarily utilized in research involving venous thromboembolism and stroke prevention in patients with atrial fibrillation. The deuterium labeling facilitates advanced metabolic studies and pharmacokinetic assessments.
Product Information
Catalog NumA77909
FormulaC34H30D11N7O5
Molecular Weight638.80
CAS Number2469006-94-6
SMILESO=C(N(C1=NC=CC=C1)CCC(OCC)=O)C2=CC=C3C(N=C(N3C)CNC4=CC=C(C=C4)C(NC(OCC([2H])(C([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])[2H])=O)=N)=C2
SynonymsBIBR 1048-d11
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Isotope-Labeled Compounds