Daclatasvir-d6 is a deuterium-labeled derivative of Daclatasvir, a highly effective antagonist of the HCV NS5A protein, exhibiting EC50 values between 9-146 pM across various HCV replicon genotypes. Additionally, Daclatasvir serves as an inhibitor of organic anion transporting polypeptide 1B (OATP1B) and OATP1B3, with IC50 values of 1.5 μM and 3.27 μM, respectively. This labeled compound is valuable for studying the pharmacokinetics and metabolic pathways of Daclatasvir in research applications related to hepatitis C virus therapy.
Daclatasvir-d6 is a deuterium-labeled derivative of Daclatasvir, a highly effective antagonist of the HCV NS5A protein, exhibiting EC50 values between 9-146 pM across various HCV replicon genotypes. Additionally, Daclatasvir serves as an inhibitor of organic anion transporting polypeptide 1B (OATP1B) and OATP1B3, with IC50 values of 1.5 μM and 3.27 μM, respectively. This labeled compound is valuable for studying the pharmacokinetics and metabolic pathways of Daclatasvir in research applications related to hepatitis C virus therapy.
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