DB04760

Catalog No.: A18548

MMP-13 inhibitor

DB04760

DB04760 Chemical Structure

CAS NO. 544678-85-5

DB04760 (compound 4) is a potent, highly selective, non-zinc-chelating MMP-13 inhibitor with an IC50 of 8 nM. DB04760 significantly reduces paclitaxel neurotoxicity and has anticancer activity.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

DB04760 (compound 4) is a potent, highly selective, non-zinc-chelating MMP-13 inhibitor with an IC50 of 8 nM. DB04760 significantly reduces paclitaxel neurotoxicity and has anticancer activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.37 mL 121.83 mL 243.65 mL
0.5 mM 4.87 mL 24.37 mL 48.73 mL
1 mM 2.44 mL 12.18 mL 24.37 mL
5 mM 0.49 mL 2.44 mL 4.87 mL

*The above data is based on the productmolecular weight 410.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18548
Actions Inhibitor
M. Wt 410.42
Formula C22H20F2N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 544678-85-5
Synonyms DB 04760, DB-04760
SMILES FC1=C(C=C(C=C1)CNC(C2=CC(C(NCC3=CC=C(C(C)=C3)F)=O)=NC=N2)=O)C

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