DBCO-NHCO-PEG6-Biotin is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). It features a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, enabling the conjugation of biotin for enhanced target protein degradation. This reagent is ideal for applications in chemical biology and drug discovery, particularly in the development of advanced therapeutic modalities.
DBCO-NHCO-PEG6-Biotin is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). It features a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, enabling the conjugation of biotin for enhanced target protein degradation. This reagent is ideal for applications in chemical biology and drug discovery, particularly in the development of advanced therapeutic modalities.
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