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DBCO-(PEG)3-VC-PAB-MMAE

Catalog No.: A41348
Drug-Linker Conjugate for ADC
DBCO-(PEG)3-VC-PAB-MMAE is a drug-linker conjugate designed for antibody-drug conjugates (ADCs). This compound features Monomethyl auristatin E (MMAE) linked to a DBCO-(PEG)3-VC-PAB structure, facilitating targeted drug delivery in cancer research. As a click chemistry reagent, it utilizes a DBCO group that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, making it valuable in bioconjugation applications.
DBCO-(PEG)3-VC-PAB-MMAE 2754384-60-4 Drug-Linker Conjugate for ADC
Grouped product items
Size Price Stock Qty
1mg
$320.00
In stock
5mg
$655.00
In stock
10mg
$1,075.00
In stock
25mg
$1,930.00
In stock
50mg
$2,830.00
In stock
100mg
$3,865.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDBCO-(PEG)3-VC-PAB-MMAE is a drug-linker conjugate designed for antibody-drug conjugates (ADCs). This compound features Monomethyl auristatin E (MMAE) linked to a DBCO-(PEG)3-VC-PAB structure, facilitating targeted drug delivery in cancer research. As a click chemistry reagent, it utilizes a DBCO group that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, making it valuable in bioconjugation applications.
Product Information
Catalog NumA41348
FormulaC86H124N12O18
Molecular Weight1613.97
CAS Number2754384-60-4
SMILESCC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCNC(CCC(N(C4)C5=C(C=CC=C5)C#CC6=C4C=CC=C6)=O)=O)=O)=O)=O)C=C3)=O)C)=O)=O)C
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC
Click Chemistry > DBCO