Monomethyl auristatin E

Catalog No.: A12954

Monomethyl auristatin E

Monomethyl auristatin E Chemical Structure

CAS NO. 474645-27-7

Monomethyl auristatin E (MMAE) is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin, and also shows inhibition of antibody-drug conjugates (ADCs) activity.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $120.00

Special Price $108.00

10 mg

Regular Price: $180.00

Special Price $162.00

25 mg

Regular Price: $280.00

Special Price $252.00

50 mg

Regular Price: $480.00

Special Price $432.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Monomethyl auristatin E (MMAE) is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin, and also shows inhibition of antibody-drug conjugates (ADCs) activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.93 mL 69.64 mL 139.28 mL
0.5 mM 2.79 mL 13.93 mL 27.86 mL
1 mM 1.39 mL 6.96 mL 13.93 mL
5 mM 0.28 mL 1.39 mL 2.79 mL

*The above data is based on the productmolecular weight 717.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A12954
Actions Stimulator
M. Wt 717.98
Formula C39H67N5O7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 474645-27-7
Synonyms Monomethylauristatin E, MMAE
SMILES CC[[email protected]](C)[[email protected]@H]([[email protected]@H](CC(=O)N1CCC[[email protected]]1[[email protected]@H]([[email protected]@H](C)C(=O)N[[email protected]](C)[[email protected]](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[[email protected]](C(C)C)NC(=O)[[email protected]](C(C)C)NC

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