DBCO-PEG3-acid is a non-cleavable ADC linker featuring a 3-unit polyethylene glycol (PEG) chain. Its primary mechanism involves the strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, enabling effective conjugation in the synthesis of antibody-drug conjugates (ADCs). This reagent is particularly valuable in therapeutic research applications, facilitating targeted drug delivery and enhancing the pharmacological properties of antibody-based treatments.
DBCO-PEG3-acid is a non-cleavable ADC linker featuring a 3-unit polyethylene glycol (PEG) chain. Its primary mechanism involves the strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, enabling effective conjugation in the synthesis of antibody-drug conjugates (ADCs). This reagent is particularly valuable in therapeutic research applications, facilitating targeted drug delivery and enhancing the pharmacological properties of antibody-based treatments.
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