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DBCO-PEG3-oxyamine

Catalog No.: A42658
ADC Linker
DBCO-PEG3-oxyamine is a non-cleavable linker specifically designed for antibody-drug conjugate (ADC) synthesis. Featuring a DBCO moiety, this reagent facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing molecules. Its application in conjugating antibodies to therapeutic agents enhances targeted delivery and efficacy in cancer research and drug development.
DBCO-PEG3-oxyamine 2748394-67-2 ADC Linker
Grouped product items
Size Price Stock Qty
5mg
$80.00
In stock
10mg
$135.00
In stock
25mg
$295.00
In stock
50mg
$480.00
In stock
100mg
$770.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDBCO-PEG3-oxyamine is a non-cleavable linker specifically designed for antibody-drug conjugate (ADC) synthesis. Featuring a DBCO moiety, this reagent facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing molecules. Its application in conjugating antibodies to therapeutic agents enhances targeted delivery and efficacy in cancer research and drug development.
Product Information
Catalog NumA42658
FormulaC29H36N4O7
Molecular Weight552.62
CAS Number2748394-67-2
SMILESO=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(NCCOCCOCCOCCNC(CON)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > ADC Linker
Click Chemistry > DBCO