DBCO-S-S-acid

Catalog No.: A43240
ADC Linker
DBCO-S-S-acid is a cleavable linker designed for the construction of antibody-drug conjugates (ADCs). It features a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, allowing for selective and efficient conjugation. This reagent is essential in bioconjugation strategies aimed at enhancing targeted therapeutic delivery in cancer research and other therapeutic applications.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDBCO-S-S-acid is a cleavable linker designed for the construction of antibody-drug conjugates (ADCs). It features a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, allowing for selective and efficient conjugation. This reagent is essential in bioconjugation strategies aimed at enhancing targeted therapeutic delivery in cancer research and other therapeutic applications.
Product Information
Catalog NumA43240
FormulaC24H24N2O4S2
Molecular Weight468.59
CAS Number2749426-25-1
SMILESO=C(CCC(NCCSSCCC(O)=O)=O)N1C(C=CC=C2)=C2C#CC(C=CC=C3)=C3C1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2