DEAE-Dextran (MW 500000) is a cationic carbohydrate polymer modified with diethylaminoethyl (DEAE) groups, facilitating the transfection of nucleic acids, including DNA and RNA, into cells. Its positive charge enhances interaction with negatively charged cell membranes, promoting efficient uptake. Additionally, DEAE-Dextran serves as an ion-exchange chromatography resin, enabling the separation and purification of biomolecules based on charge properties. This reagent is widely utilized in biochemical assays and molecular biology applications.
DEAE-Dextran (MW 500000) is a cationic carbohydrate polymer modified with diethylaminoethyl (DEAE) groups, facilitating the transfection of nucleic acids, including DNA and RNA, into cells. Its positive charge enhances interaction with negatively charged cell membranes, promoting efficient uptake. Additionally, DEAE-Dextran serves as an ion-exchange chromatography resin, enabling the separation and purification of biomolecules based on charge properties. This reagent is widely utilized in biochemical assays and molecular biology applications.
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