Delgocitinib ethanolate is a selective inhibitor of Janus kinases (JAKs), demonstrating IC50 values of 2.8 nM for JAK1, 2.6 nM for JAK2, 13 nM for JAK3, and 58 nM for Tyk2. This compound effectively modulates signaling pathways associated with inflammatory responses and immune regulation. It is primarily used in research applications involving autoimmune diseases and other conditions where JAK signaling is implicated.
Delgocitinib ethanolate is a selective inhibitor of Janus kinases (JAKs), demonstrating IC50 values of 2.8 nM for JAK1, 2.6 nM for JAK2, 13 nM for JAK3, and 58 nM for Tyk2. This compound effectively modulates signaling pathways associated with inflammatory responses and immune regulation. It is primarily used in research applications involving autoimmune diseases and other conditions where JAK signaling is implicated.
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