Desmethyl Erlotinib-d4

Catalog No.: A70863
Stable Isotope
Desmethyl Erlotinib-d4 is a deuterium-labeled form of Desmethyl Erlotinib, an active metabolite of the potent EGFR tyrosine kinase inhibitor Erlotinib. This stable isotope serves as a valuable tool in pharmacokinetic studies and can be utilized in click chemistry applications, particularly in copper-catalyzed azide-alkyne cycloaddition (CuAAc). The incorporation of an alkyne group enables specific labeling and tracking of biomolecules in various research contexts.
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Size Price Stock Qty
1mg
$895.00
In stock
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDesmethyl Erlotinib-d4 is a deuterium-labeled form of Desmethyl Erlotinib, an active metabolite of the potent EGFR tyrosine kinase inhibitor Erlotinib. This stable isotope serves as a valuable tool in pharmacokinetic studies and can be utilized in click chemistry applications, particularly in copper-catalyzed azide-alkyne cycloaddition (CuAAc). The incorporation of an alkyne group enables specific labeling and tracking of biomolecules in various research contexts.
Product Information
Catalog NumA70863
FormulaC21H17D4N3O4
Molecular Weight383.43
CAS Number1216420-11-9
SMILESN(C=1C2=C(C=C(OCCOC)C(OCCO)=C2)N=CN1)C3=C(C(C#C)=C(C(=C3[2H])[2H])[2H])[2H]
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