Desvenlafaxine-d10 is a deuterated version of Desvenlafaxine, which is the active metabolite of Venlafaxine. It functions primarily as a selective inhibitor of the serotonin and norepinephrine transporters (5-HT and NET), demonstrating IC50 values of 47.3 nM and 531.3 nM, respectively. This compound is utilized in pharmacokinetic studies and research involving neurotransmitter systems, given its ability to penetrate the blood-brain barrier and its limited interaction with the dopamine transporter, where it exhibits only weak inhibitory activity.
Desvenlafaxine-d10 is a deuterated version of Desvenlafaxine, which is the active metabolite of Venlafaxine. It functions primarily as a selective inhibitor of the serotonin and norepinephrine transporters (5-HT and NET), demonstrating IC50 values of 47.3 nM and 531.3 nM, respectively. This compound is utilized in pharmacokinetic studies and research involving neurotransmitter systems, given its ability to penetrate the blood-brain barrier and its limited interaction with the dopamine transporter, where it exhibits only weak inhibitory activity.
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