Didesmethyl cariprazine-d8 is a deuterium-labeled derivative of didesmethyl cariprazine, a metabolite of the antipsychotic drug Cariprazine. This compound acts as a partial agonist at dopamine D2 and D3 receptors, a full agonist at the serotonin 5-HT1A receptor, and an antagonist at the 5-HT2B receptor. Its activity has been shown to dose-dependently inhibit the spontaneous firing of rat midbrain dopaminergic neurons, making it valuable for research in psychiatric disorders and neuropharmacology.
Didesmethyl cariprazine-d8 is a deuterium-labeled derivative of didesmethyl cariprazine, a metabolite of the antipsychotic drug Cariprazine. This compound acts as a partial agonist at dopamine D2 and D3 receptors, a full agonist at the serotonin 5-HT1A receptor, and an antagonist at the 5-HT2B receptor. Its activity has been shown to dose-dependently inhibit the spontaneous firing of rat midbrain dopaminergic neurons, making it valuable for research in psychiatric disorders and neuropharmacology.
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