Fig. 1 · Structure
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Dimethyl malonate
SDH Inhibitor
Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH) that effectively crosses the blood-brain barrier and hydrolyzes to malonate. This compound plays a crucial role in reducing neuronal apoptosis, making it valuable in studies related to neuroprotection and metabolic disorders. Its ability to modulate SDH activity positions dimethyl malonate as a significant reagent for research in cellular respiration and associated pathological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 108-59-8 |
| Applications | SDH Inhibitor |
| Formula | C5H8O4 |
| Molecular Weight | 132.11 |
| SMILES | O=C(OC)CC(OC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.