DMP-851 is a potent cyclic urea inhibitor of HIV protease, exhibiting a Ki of 0.021 nM. It demonstrates significant antiviral activity against both laboratory strains of HIV-1 and HIV-2, as well as primary clinical isolates that are resistant to Zidovudine. This compound serves as an important tool for research into HIV treatment and resistance mechanisms.
DMP-851 is a potent cyclic urea inhibitor of HIV protease, exhibiting a Ki of 0.021 nM. It demonstrates significant antiviral activity against both laboratory strains of HIV-1 and HIV-2, as well as primary clinical isolates that are resistant to Zidovudine. This compound serves as an important tool for research into HIV treatment and resistance mechanisms.
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