Catalog No.: A11847

Thymidine phosphorylase activator


Doxifluridine Chemical Structure

CAS NO. CAS: 3094-09-5

Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM.

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  • Takashi Azuma, .et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
  • Azuma T, .et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
  • Azuma T, .et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347

Biological Activity

Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM.
In vitro DMSO 44 mg/mL (178.72 mM)
Water 44 mg/mL (178.72 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 40.62 mL 203.1 mL 406.19 mL
0.5 mM 8.12 mL 40.62 mL 81.24 mL
1 mM 4.06 mL 20.31 mL 40.62 mL
5 mM 0.81 mL 4.06 mL 8.12 mL

*The above data is based on the productmolecular weight 246.19. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11847
Actions Activator
CAS No. CAS: 3094-09-5
Formula C9H11FN2O5
M. Wt 246.19
Purity >98%
Synonyms Ro 21-9738, 5-Fluoro-5'-deoxyuridine, 5'-DFUR

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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