Doxifluridine

Catalog No.: A11847

Thymidine phosphorylase activator

Doxifluridine

Doxifluridine Chemical Structure

CAS NO. CAS: 3094-09-5

Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM.

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  • Takashi Azuma, .et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
  • Azuma T, .et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
  • Azuma T, .et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347

Biological Activity

Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 40.62 mL 203.1 mL 406.19 mL
0.5 mM 8.12 mL 40.62 mL 81.24 mL
1 mM 4.06 mL 20.31 mL 40.62 mL
5 mM 0.81 mL 4.06 mL 8.12 mL

*The above data is based on the productmolecular weight 246.19. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11847
Actions Activator
M. Wt 246.19
Formula C9H11FN2O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. CAS: 3094-09-5
Synonyms Ro 21-9738, 5-Fluoro-5'-deoxyuridine, 5'-DFUR
SMILES CC1C(C(C(O1)N2C=C(C(=O)NC2=O)F)O)O

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