Fig. 1 · Structure

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Droxidopa hydrochloride

Norepinephrine Precursor

Droxidopa hydrochloride is a potent orally active norepinephrine precursor. It effectively increases standing blood pressure and alleviates symptoms associated with orthostatic hypotension, thereby enhancing standing ability. This compound holds potential for research into neurogenic orthostatic hypotension (nOH) and may provide insights into alternative treatments for attention deficit hyperactivity disorder (ADHD).

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1260173-94-1
Applications Norepinephrine Precursor
Formula C9H12ClNO5
Molecular Weight 249.65
Synonyms L-DOPS hydrochloride; DOPS hydrochloride; SM5688 hydrochloride
SMILES
OC1=C(O)C=CC([C@@H](O)[C@@H](C(O)=O)N)=C1.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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