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DTNP

Fluorescent probe

DTNP is a BchE-activated near infrared (NIR) fluorescent probe known for its ability to permeate the blood-brain barrier. Upon activation by butyrylcholinesterase (BchE), DTNP exhibits inhibitory effects on enzyme activity, making it a valuable tool in the study of Alzheimer's disease (AD). Its unique properties facilitate research into the pathological mechanisms and potential therapeutic strategies related to neurodegeneration.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3010266-66-4
Applications	Fluorescent probe
Formula	C₆₃H₆₇IN₈O₆
Molecular Weight	1159.16
SMILES	CC1(C(/C=C/C(CCC2)=C3C2=CC4=C(O3)C=C(OC(C5CC5)=O)C=C4)=[N+](C6=CC=CC=C61)CCCC7=CN(CCNC(C8=CC=CC(C(NC9=CC=CC(C(NCC%10=CC=CC=C%10CN(CC)CC)=O)=C9)=O)=C8)=O)N=N7)C.[I-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.