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Browse substrates and optical reporter reagents for enzyme-activity assays. Enzyme-activated fluorogenic probes can convert a chemical transformation into a fluorescence readout.[1] Choose the exact reagent for your enzyme, sample and detection method, and distinguish fluorescent from color-based readouts. This collection does not imply that every substrate is selective for one enzyme or suitable for use in living cells.
[1] Chyan W, Raines RT. Enzyme-Activated Fluorogenic Probes for Live-Cell and in Vivo Imaging. ACS Chemical Biology. 2018;13(7):1810–1823. DOI: 10.1021/acschembio.8b00371. PMID: 29924581; PMCID: PMC6056172.
Chromozym t-PA is a substrate specifically designed for the quantification of tissue plasminogen activator (t-PA) concentration. It enables sensitive measurement of t-PA activity, facilitating research in coagulation and fibrinolysis studies. This reagent is suitable for various applications, including diagnostic assays and the evaluation of therapeutic strategies targeting the fibrinolytic system.
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