Fig. 1 · Structure
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EBOV-IN-7
EBOV Inhibitor
EBOV-IN-7 is a selective inhibitor of the Ebola virus (EBOV), displaying an IC50 of 2.04 μM against EBOV glycoprotein (EBOV-GP) pseudotyped virus. This compound disrupts the interaction between EBOV-GP and NPC1, which is crucial for viral entry. Additionally, EBOV-IN-7 exhibits inhibitory effects on cancer cell proliferation, making it a valuable tool for research in virology and oncology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 68207-16-9 |
| Applications | EBOV Inhibitor |
| Formula | C18H19ClN4O3S |
| Molecular Weight | 406.89 |
| SMILES | O=C(NNC1=CC=CC=C1SC2=CC(Cl)=CC=C2[N+]([O-])=O)CN3CCCC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.