Fig. 1 · Structure
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Ecopipam hydrobromide
D1/D5 Antagonist
Ecopipam hydrobromide is a highly selective antagonist of dopamine D1 and D5 receptors, exhibiting dissociation constants (Kis) of 1.2 nM and 2.0 nM, respectively. It demonstrates over 40-fold selectivity compared to D2, D4, 5-HT, and α2a receptors. This compound is valuable for research investigating the pathophysiology of schizophrenia and obesity, making it a useful tool for studying dopaminergic signaling pathways and related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2587360-22-1 |
| Applications | D1/D5 Antagonist |
| Formula | C19H21BrClNO |
| Molecular Weight | 394.73 |
| Synonyms | SCH 39166 hydrobromide |
| SMILES | CN1[C@]2([H])[C@@](C3=CC=CC=C3CC2)([H])C4=CC(O)=C(Cl)C=C4CC1.Br |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.