Fig. 1 · Structure
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EGTA tetrasodium
Calcium Ion Chelator
EGTA tetrasodium is a specialized calcium ion chelator with a primary mechanism of chelating Ca2+ ions. It exhibits a low apparent calcium dissociation constant (Kd) of 60.5 nM at physiological pH (7.4), demonstrating high specificity for calcium over magnesium (Kd for Mg2+ is 1-10 mM). This compound is utilized in research applications focusing on calcium-dependent cellular processes, including the inhibition of substrate adherence in inflammatory macrophages.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 13368-13-3 |
| Applications | Calcium Ion Chelator |
| Formula | C14H20N2Na4O10 |
| Molecular Weight | 468.28 |
| SMILES | O=C(O[Na])CN(CC(O[Na])=O)CCOCCOCCN(CC(O[Na])=O)CC(O[Na])=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.