ELAAWCRWGFLLALLPPGIAG

Catalog No.: A28735
Peptide
ELAAWCRWGFLLALLPPGIAG is a peptide derived from the rat HER2/neu protein, comprising 21 amino acids (aa 5-25). It has been demonstrated to induce cytotoxic T lymphocyte (CTL) responses in mice with HER2-positive tumors, making it a valuable tool for studying immune responses in cancer therapy. This peptide is particularly relevant for research applications focused on immunotherapy and the modulation of tumor-specific immune responses.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionELAAWCRWGFLLALLPPGIAG is a peptide derived from the rat HER2/neu protein, comprising 21 amino acids (aa 5-25). It has been demonstrated to induce cytotoxic T lymphocyte (CTL) responses in mice with HER2-positive tumors, making it a valuable tool for studying immune responses in cancer therapy. This peptide is particularly relevant for research applications focused on immunotherapy and the modulation of tumor-specific immune responses.
Product Information
Catalog NumA28735
FormulaC109H164N26O24S
Molecular Weight2254.69
CAS Number1443436-78-9
SequenceGlu-Leu-Ala-Ala-Trp-Cys-Arg-Trp-Gly-Phe-Leu-Leu-Ala-Leu-Leu-Pro-Pro-Gly-Ile-Ala-Gly
Sequence shorteningELAAWCRWGFLLALLPPGIAG
SMILESC([C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC=1C=2C(NC1)=CC=CC2)C(NCC(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(=O)N5[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(O)=O)=O)C)=O)[C@H](CC)C)=O)=O)CCC5)CCC4)CC(C)C)=O)CC(C)C)=O)C)=O)CC(C)C)=O)CC(C)C)=O)=O)=O)=O)CCCNC(=N)N)=O)CS)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)N)=O)CC(C)C)=O)C)=O)C)=O)C=6C=7C(NC6)=CC=CC7
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