EN6

Catalog No.: A18524

Autophagy activator

EN6

EN6 Chemical Structure

CAS NO. 1808714-73-9

EN6 is a novel covalent autophagy activator, targeting cysteine 277 in the ATP6V1A subunit of the lysosomal v-ATPase, which activates mTORC1 via the Rag guanosine triphosphatases.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$155.00
50 mg
$460.00
100 mg
$920.00
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Biological Activity

EN6 is a novel covalent autophagy activator, targeting cysteine 277 in the ATP6V1A subunit of the lysosomal v-ATPase, which activates mTORC1 via the Rag guanosine triphosphatases.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.15 mL 135.74 mL 271.49 mL
0.5 mM 5.43 mL 27.15 mL 54.3 mL
1 mM 2.71 mL 13.57 mL 27.15 mL
5 mM 0.54 mL 2.71 mL 5.43 mL

*The above data is based on the productmolecular weight 368.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18524
Actions Activator
M. Wt 368.34
Formula C19H14F2N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1808714-73-9
Synonyms EN6; EN-6; EN 6
SMILES O=C(C1=CN(C2=CC=CC=C2F)N=C1)NC3=CC=C(F)C(NC(C=C)=O)=C3

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