Fig. 1 · Structure

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endo-BCN-PEG3-NH-Boc

PROTAC Linker

endo-BCN-PEG3-NH-Boc serves as a PEG-based linker specifically designed for PROTAC (proteolysis-targeting chimeras) applications. This compound facilitates the synthesis of PROTACs by enabling conjugation between target proteins and E3 ligases, thereby promoting ubiquitination and subsequent degradation of designated proteins. Its chemical structure allows for improved solubility and stability in biological systems, making it a valuable tool in chemical biology and drug discovery research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1807501-84-3
Applications PROTAC Linker
Formula C24H40N2O7
Molecular Weight 468.58
SMILES
O=C(OCC1C2CCC#CCCC12)NCCOCCOCCOCCNC(OC(C)(C)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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