endo-BCN-PEG4-acid

Catalog No.: A42703
ADC Linker
endo-BCN-PEG4-acid is a versatile cleavable linker designed for antibody-drug conjugates (ADCs), facilitating targeted drug delivery. Featuring a bicyclo[6.1.0]nonyne (BCN) moiety, this compound enables efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. It is particularly useful in bioconjugation and drug development applications, allowing for the precise attachment of therapeutic agents to antibodies.
Grouped product items
Size Price Stock Qty
50mg
$120.00
In stock
100mg
$190.00
In stock
250mg
$465.00
In stock
1g
$1,390.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionendo-BCN-PEG4-acid is a versatile cleavable linker designed for antibody-drug conjugates (ADCs), facilitating targeted drug delivery. Featuring a bicyclo[6.1.0]nonyne (BCN) moiety, this compound enables efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. It is particularly useful in bioconjugation and drug development applications, allowing for the precise attachment of therapeutic agents to antibodies.
Product Information
Catalog NumA42703
FormulaC22H35NO8
Molecular Weight441.52
CAS Number1881221-47-1
SMILESO=C(O)CCOCCOCCOCCOCCNC(OC[C@H]1[C@@]2([H])CCC#CCC[C@@]12[H])=O
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