Fig. 1 · Structure
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endo-BCN-PEG4-NHS ester
PROTAC Linker
endo-BCN-PEG4-NHS ester is a PEG-based PROTAC linker specifically designed for the synthesis of PROTACs. This compound features a BCN group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. It plays a crucial role in the development of targeted protein degradation strategies and is suitable for applications in drug discovery and chemical biology research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2252422-32-3 |
| Applications | PROTAC Linker |
| Formula | C26H38N2O10 |
| Molecular Weight | 538.59 |
| SMILES | O=C(OCC1C2CCC#CCCC12)NCCOCCOCCOCCOCCC(ON3C(CCC3=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.