Biological Activity
Entacapone is a specific, potent, peripherally acting catechol-O-methyltransferase (COMT) inhibitor with IC50 of 151 nM for PD treatment.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 30.56 mL | 152.78 mL | 305.56 mL |
0.5 mM | 6.11 mL | 30.56 mL | 61.11 mL |
1 mM | 3.06 mL | 15.28 mL | 30.56 mL |
5 mM | 0.61 mL | 3.06 mL | 6.11 mL |
*The above data is based on the productmolecular weight 327.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A21888 |
---|---|
Actions | Inhibitor |
CAS No. | 1047659-02-8 |
Formula | C14H14N3NaO5 |
M. Wt | 327.27 |
Purity | >98% |
Synonyms | ADX47273, ADX 47273 |
SMILES | O=C(N(CC)CC)/C(C#N)=C/C1=CC([N+]([O-])=O)=C([O-])C(O)=C1.[Na+] |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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