(-)-Epicatechin gallate

Catalog No.: A12044

(-)-Epicatechin gallate

(-)-Epicatechin gallate Chemical Structure

CAS NO. 1257-08-5

(-)Epicatechin gallate is a polyphenol apoptosis inducer in tumor cells commonly found in green tea.

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  • A S D'Costa, .et al. Inhibition of starch digestion by flavonoids: Role of flavonoid-amylase binding kinetics, Food Chem, 2020, Oct 1;341(Pt 2):128256 PMID: 33035827
  • Fenteany G, .et al. Multilevel structure-activity profiling reveals multiple green tea compound families that each modulate ubiquitin-activating enzyme and ubiquitination by a distinct mechanism, Sci Rep, 2019, Sep 5;9(1):12801 PMID: 31488855
  • Mihaela Tudorache, .et al. Phenolic compounds mediate aggregation of water-soluble polysaccharides and change their rheological properties: Effect of different phenolic compounds, Food Hydrocoll, 2019, 97, Dec, 105193

Biological Activity

(-)Epicatechin gallate is a polyphenol apoptosis inducer in tumor cells commonly found in green tea.
In vitro DMSO 78 mg/mL (176.32 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.61 mL 113.03 mL 226.06 mL
0.5 mM 4.52 mL 22.61 mL 45.21 mL
1 mM 2.26 mL 11.3 mL 22.61 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12044
CAS No. 1257-08-5
Formula C22H18O10
M. Wt 442.37
Solubility DMSO
Purity >98%
Synonyms (-)Epicatechin gallate, (-)-Epicatechin-3-O-gallate
SMILES C1[[email protected]]([[email protected]](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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