Erastin

Catalog No.: A13822
VDAC inhibitor
Erastin is a cell-permeable piperazinyl-quinazolinone compound that exhibits oncogene-selective lethality in cells with H-Ras mutations.
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Product Name Price Stock Qty
Erastin 5mg
Special Price $56.00 Regular Price $70.00
In stock
Erastin 10mg
Special Price $96.00 Regular Price $120.00
In stock
Erastin 25mg
Special Price $200.00 Regular Price $250.00
In stock
Erastin 50mg
Special Price $280.00 Regular Price $350.00
In stock
Erastin 10mM * 1mL in DMSO
Special Price $108.00 Regular Price $135.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Erastin has been cited by 3 publications
  • Erva Ozkan, .et al. , Life Sci, 2023, Jan 1;312:121222 PMID: 36442526
  • Yuki Shibata, .et al. , Biochem Biophys Rep, 2021, Feb 24;26 PMID: 33681481
  • Shibata Y, .et al. , PLoS One, 2019, Dec 4;14(12):e0225931 PMID: 31800616
  • Biological Activity
    Discription Erastin is a cell-permeable piperazinyl-quinazolinone compound that exhibits oncogene-selective lethality in cells with H-Ras mutations.
    Targets
    Target Value
    Product Information
    Catalog Num A13822
    Formula C30H31ClN4O4
    Molecular Weight 547.04
    CAS Number 571203-78-6
    SMILES CCOC1=CC=CC=C1N2C(=O)C3=CC=CC=C3N=C2C(C)N4CCN(CC4)C(=O)COC5=CC=C(C=C5)Cl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 17 mg/mL (31.07 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5%DMSO+40%PEG 300+5%Tween80+ddH2O 1.66 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.28 mL 91.4 mL 182.8 mL
    0.5 mM 3.66 mL 18.28 mL 36.56 mL
    1 mM 1.83 mL 9.14 mL 18.28 mL
    5 mM 0.37 mL 1.83 mL 3.66 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

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