Erastin

Catalog No.: A13822

VDAC inhibitor

Erastin Chemical Structure

CAS NO. 571203-78-6

Erastin is a cell-permeable piperazinyl-quinazolinone compound that exhibits oncogene-selective lethality in cells with H-Ras mutations.

Availability: In stock

Package Price Qty
5 mg
$70.00
10 mg
$120.00
25 mg
$250.00
50 mg
$350.00
10mM * 1mL in DMSO
$135.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Erastin is a cell-permeable piperazinyl-quinazolinone compound that exhibits oncogene-selective lethality in cells with H-Ras mutations.
Targets
Ferroptosis
In vitro DMSO 19 mg/mL (34.73 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.28 mL 91.4 mL 182.8 mL
0.5 mM 3.66 mL 18.28 mL 36.56 mL
1 mM 1.83 mL 9.14 mL 18.28 mL
5 mM 0.37 mL 1.83 mL 3.66 mL

*The above data is based on the productmolecular weight 547.04. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13822
Actions Inhibitor
M. Wt 547.04
Formula C30H31ClN4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 571203-78-6
Synonyms N/A
SMILES CCOC1=CC=CC=C1N2C(=O)C3=CC=CC=C3N=C2C(C)N4CCN(CC4)C(=O)COC5=CC=C(C=C5)Cl

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